New gene drive reverses insecticide resistance in pests
spraying insecticides - ugh!
New gene drive reverses insecticide resistance in pests... but then disappears !!!
University of California San Diego geneticists have developed a gene drive-based solution to the widespread problem of insecticide resistance. In an effort to protect valuable crops, the researchers created an 'e-Drive' that reverses insecticide resistance and then disappears from the insect population.
The self-eliminating 'e-Drive' replaces the mutant genes with native genes to reduce pesticide use and protect valuable food crops.
Gene replacement using "alleles"
Resistance
Chemical insecticides have been used for centuries to control pest damage to valuable food crops. Eventually, over time, beetles, moths, flies and other insects develop genetic mutations that render the insecticide chemicals ineffective.
Response
The increased resistance by these insects forces farmers to ramp up use of poisonous compounds at increasing frequencies and concentrations. This increases the risks to human health and damage to the environment since most insecticides kill both ecologically important insects as well as pests.
New Solutions
To help counter these problems, researchers developed powerful technologies that genetically remove insecticide-resistant variant genes and replace them with the original genes that are susceptible to pesticides. These gene-drive technologies, based on CRISPR gene editing, have the potential to protect valuable crops and vastly reduce the amount of chemical pesticides required to eliminate pests.
The main concern has always been the unknown risks of these genes once they are released into a population as they could continuously spread unchecked. Their method converts insecticide-resistant forms of mutated insect genes back to their natural, native form. The system is designed to spread the original "wild type" version of the gene and then disappear, leaving only a population of insects with the corrected version of the gene.
The researchers said that the self-eliminating nature of the e-Drive means it can be introduced and re-introduced as needed. The researchers are now also developing an e-Drive system in mosquitoes to help prevent the spread of malaria.
We at Plant Specialists are all for using less pesticides - anywhere !
This idea for this article came from someone in our accounting team
- even our accountants are plant people !!!
PLANT SPECIALISTS
GREENING NEW YORK FOR OVER 53 YEARS !
Article written by our Staff Horticulturist, Peter B Morris, BSc, MSc, MBA
All photographs used with permission @SHUTTERSTOCK